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Topics in Evidence-Based Pharmacy Practice
7/18/2012: Haloperidol Prophylaxis Decreases Delirium Incidence in Elderly
Patients after Non-Cardiac Surgery
Nada Al-Qadheeb
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Excerpt:"More than 5,000,000 patients are admitted to an intensive care unit (ICU) in the United States each year and up to 80% of these patients who are mechanically ventilated develop delirium.1,2 Delirium is often associated with poor functional recovery, more frequent complications, longer hospital stays and higher mortality. In fact, after controlling for preexisting morbidities, severity of illness, coma, and use of sedatives, patients who develop delirium in the ICU are more than 3-times as likely to be dead at 6 months compared to those patients who do not develop delirium.1-5 It is therefore critical that interventions that can prevent delirium from occurring in the ICU be discovered. ..."
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