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Updates & EBPP 
                  









Topics in Evidence-Based Pharmacy Practice is a continually updated collection of features and editorials that review, examine, and comment on the overload of information in the pharmacy field. Features are reviews of clinical trials, studies, and guidelines that examine the validity of approach, methodology, results, and recommendations, and make recommendations that can affect decision making. Editorials allow leading and emerging minds in the field express their opinion on the ever-changing world of pharmacy practice.

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5/15/2013
Low-Dose Aspirin: Can It Prevent Recurrent Venous Thromboembolism?
by Hargbol, Alexis; Rager, Michelle


5/13/2013
Risk Stratification and the Use of Apixaban for Stroke Prevention in Atrial Fibrillation
by Dearing, Natalie


5/7/2013
Inhaled Anticholinergics for Asthma? Don’t Hold Your Breath (Yet)
by Adams, Solomon; Falter, Rebecca


4/30/2013
Will Young People with Primary Mediastinal B-Cell Lymphoma Be Cured? The Dose-Adjusted EPOCH-Rituximab Therapy Story.
by Alotaibi, Ghazi


4/29/2013
Pain, Agitation and Delirium: What Has Changed since 2002?
by Al-Qadheeb, Nada


4/26/2013
The Magical Drugs are No Longer Magical: Steroids and Risk of Venous Thromboembolism.
by Alotaibi, Ghazi


4/26/2013
Beware: A Novel Avian-Origin Flu Virus is Back in 2013
by Al-Qadheeb, Nada


4/11/2013
Acute Respiratory Distress Syndrome:  A New 2012 Definition!
by Al-Qadheeb, Nada


4/11/2013
Vasopressin vs. Norepinephrine for Resuscitation in Septic Shock?
by Al-Qadheeb, Nada


3/26/2013
How Much Is Too Much? Single Acetaminophen Toxicity Is Better Than Chronic Toxicity in Children
by Alotaibi, Ghazi


3/18/2013
Dabigatran in Stroke Prevention: Is It Worth The Money?
by Alotaibi, Ghazi


3/18/2013
Preventing Type 2 Diabetes by Weight Training – Does a Barbell a Day Keep Diabetes Away?
by Lee, Rosa; Rager, Michelle


3/14/2013
Can a Statin a Day Keep Colorectal Cancer Away?  Statins for Prevention of Colorectal Cancer
by Carini, Nina; Havrda, Dawn


3/11/2013
A Promising Silver Lining for Another Oral Agent for Ulcerative Colitis?
by Asare-Wassow, Juanetta; Kim, Jenny


3/8/2013
Stress Ulcer Prophylaxis in Critically Ill Patients – PPIs or H2RAs?
by Al-Qadheeb, Nada


3/8/2013
Can We Prevent Delirium in High-Risk Critically Ill Patients?
by Al-Qadheeb, Nada


2/11/2013
Do Diabetics Benefit from Physical Activity? Does the Extra Sweat Mean Extra Years?
by Ray, Emily; Rager, Michelle


2/11/2013
Dual Antiplatelet Does Not Correlate To Twice the Effectiveness: A Look at Aspirin and Clopidogrel for Lacunar Stroke
by Fairall, Keith; Wesner, Amber


1/25/2013
Low Molecular Weight Heparin versus Unfractionated Heparin Use in the Postoperative Setting
by Alotaibi, Ghazi


1/18/2013
Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C
by Al-Qadheeb, Nada


1/14/2013
Did MONET1 Paint a New Picture for Advanced Non-Squamous Non-Small Cell Lung Cancer?
by Crawford, Aaron; Frei, Bradi


1/3/2013
Association between Colistin Dose and Microbiologic Outcomes
by Nazer, Lama


12/14/2012
Treatment for Advanced Prostate Cancer: A New Antiandrogen Shows Promise
by Adams, Solomon; Havrda, Dawn


12/3/2012
Treat Me, Treat Me Not! Neuraminidase Inhibitors for Influenza in Adults and Children
by Alotaibi, Ghazi


11/29/2012
Is PIVOT Pivotal for Prostatectomy in Localized Prostate Cancer?
by Castillo, Andrew; Frei, Bradi


11/21/2012
Do Inhaled Glucocorticoids Used In Children with Persistent Asthma Affect Adult Height?
by McKenzie, Bradley; Jawaid, Sarah


11/19/2012
Cefpodoxime as an Alternative to Ciprofloxacin in the Treatment of Acute, Uncomplicated Cystitis: A Viable Option?
by Finocchio, Brittany; Havrda, Dawn


11/15/2012
Is Increasing the Dose of Clopidogrel Effective in Clopidogrel Resistant Patients in Preventing Cardiovascular and Cerebrovascular Events Post PCI?
by Lee, Tina; Lopez, Tina


11/15/2012
Question On Evidence: Should Women Be On Statins For Secondary Prevention?
by Joseph, Merlyn; Lopez, Tina


10/23/2012
Glucose Control in the Critically Ill: An Update on the Relationship between Hypoglycemia & Mortality
by Marini, Erica


10/23/2012
Boning Up on Bones: Atypical Fractures and Bisphosphonate Use
by Anderson, Zachary


10/23/2012
Can A Fish A Day Keep the ED Away?
by Khan, Saleh; Lalama, Jeffrey


10/23/2012
Statins Role in the Prevention of Venous Thromboembolic Events: Are They the Future “Multi-Purpose” Drugs?
by Alotaibi, Ghazi; Almodaimegh, Hind


10/23/2012
Daily Sedation Interruption: Not Needed Anymore?
by Cheung, Alexandra


10/22/2012
Could Etomidate Cause Pneumonia?
by Al-Qadheeb, Nada


10/22/2012
Anti-Arrhythmic Treatment Post-Cardioversion in Atrial Fibrillation: How Long Is Enough?
by Scott, Amanda


10/22/2012
Influenza Vaccines: Efficacy and Effectiveness
by Cheung, Alexandra


10/22/2012
What Is Happening with Pharmacy Residency Training Around The World?
by Al-Qadheeb, Nada


10/19/2012
Being a Pharmacist Means Being a Leader!
by Linn, William; Trang, David


10/18/2012
Vorapaxar - A Novel Antiplatelet for Secondary Prevention after Acute Coronary Syndromes: The TRACER Trial
by Bal-Hareth, Sakra


10/18/2012
Esophageal Cancer Therapy CROSSes New Thresholds
by Frei, Bradi; James, Joshua; Lomas, Mary


10/12/2012
Does Therapy of Latent Tuberculosis Take Too Long?
by Al-Qadheeb, Nada


10/12/2012
Medication Therapy Management – What to Expect in 2013
by Havrda, Dawn


10/11/2012
Is Lifestyle Modification Futile in Adolescents with Type 2 Diabetes?
by Ricchetti, Charlotte


10/4/2012
Understanding Biostatistics Concepts among Pharmacy Residents
by Al-Qadheeb, Nada


10/4/2012
Basal Insulin Use Early in Type 2 Diabetes: The ORIGIN Trial – Does the Benefit Outweigh the Concerns?
by Jennifer Clements


9/28/2012
Medication and Appointment Compliance with Type 2 Diabetes – Is it a Life or Death Matter?
by Han, Feng; Falter, Rebecca


9/26/2012
Thiazolidinediolines in Type 2 Diabetes: To See or Not to See – Is It Worth the Risk?
by Kang, Gloria; Masters, Kelly


9/26/2012
Is Aspirin Sufficient for Preventing the Recurrence of Venous Thromboembolism?
by Low, Kimberly; Ricchetti, Charlotte


9/25/2012
Is Procalcitonin Useful for the Initiation of Antibiotics in the Intensive Care Unit?
by Al-Qadheeb, Nada


9/25/2012
Nasogastric Tube or Nasojejunal Tube for Critically Ill Patients?
by Al-Qadheeb, Nada


9/18/2012
ADOPTing VTE Prophylaxis in Medically Ill Patients Beyond Hospital Discharge
by Al-Qadheeb, Nada


9/18/2012
Is Aspirin the Magic Pill? Role in Systemic Inflammatory Response Syndrome and Sepsis in Critically Ill Patients
by Al-Qadheeb, Nada


9/18/2012
Native-Valve Infective Endocarditis–Any Role for Early Surgery?
by Al-Qadheeb, Nada


9/18/2012
Bariatric Surgery versus Intensive Medical Therapy in the Treatment of Type 2 Diabetes.
by Martin, Sarah; Rager, Michelle


9/18/2012
HTN Therapy in the Very Elderly: It Is Never Too Late!
by Linn, William


9/14/2012
LIFENOX TRIAL equals GES plus ENOXAPARIN
by Al-Qadheeb, Nada


9/12/2012
Aspirin vs. Warfarin:  The Debate Continues for Patients with Heart Failure in Sinus Rhythm
by Khan, Saleh; Lalama, Jeffrey


9/12/2012
Feeding the Critically Ill: Results of the EDEN trial
by Al-Qadheeb, Nada


9/12/2012
Systemic Antifungal Therapy in Critically Ill Patients without Invasive Fungal Infection
by Cheung, Alexandra


8/23/2012
Treating Blood Pressure after Stroke: What Should the Target Level Be?
by Wesner, Amber


8/23/2012
Medications Leading to Emergency Hospitalizations for Older Americans
by Havrda, Dawn


8/22/2012
Medications Must Resume after Hospitalization
by Beebe, Morgan; Lopez, Tina


8/22/2012
Pioglitazone for Diabetes Prevention
by Phillips, Vanessa; Lopez, Tina


8/22/2012
Going the Extra Mile, or 8 Weeks, in Patients on a Stable Warfarin Dosage
by Anderson, Zachary


8/21/2012
Will New Kids on the Block Save Patients from Few Needle Sticks? New Oral Anticoagulants Compared to Enoxaparin
by Alotaibi, Ghazi; Almodaimegh, Hind


8/13/2012
Exenatide Once-Weekly Injection: Superior to Insulin Glargine for Type 2 Diabetics?
by Nordberg, Sarah; Rager, Michelle


8/13/2012
Azithromycin and the Risk of Cardiovascular Death
by El-Lababidi, Rania


8/8/2012
Using Aspirin for Primary Prevention of Vascular and Non-Vascular Outcomes: What Are the Data?
by Lalama, Jeffrey


8/8/2012
Risk of Acute Coronary Events and Dabigatran
by Lalama, Jeffrey


8/7/2012
One Step Closer to Answering Questions Related to Vitamin D Dosing
by McMillan, Ashlee


8/7/2012
Is The End of Herpes Upon Us?
by Alam, Shabana; Adams, Erin


8/7/2012
Macrolide Use Beyond Its Antibacterial Activity!
by Al-Qadheeb, Nada


8/6/2012
Is Low Dose Warfarin Therapy Safe for Pregnant Women after Valve Replacement Surgery?
by Ricchetti, Charlotte


8/6/2012
Optimal therapy for Ischemic Stroke or Transient Ischemic Attack Associated with Patent Foramen Ovale: Device or Drug?
by Havrda, Dawn


8/6/2012
De-Escalation in Patients with Severe Nosocomial Sepsis: Is It Even Possible?
by Al-Qadheeb, Nada


8/3/2012
Continuous Infusion of Vancomycin: Is It Even an Option?
by Al-Qadheeb, Nada


8/3/2012
Feature: Dexmedetomidine vs. Midazolam or Propofol for Sedation During Prolonged Mechanical Ventilation
by Al-Qadheeb, Nada


8/3/2012
Intensive Therapy for Type 1 Diabetes: More than Glycemic Control
by Kalis, Joseph; Wright, Katrina


8/3/2012
Parenteral Nutrition: Fast and Furious!
by Al-Qadheeb, Nada


8/1/2012
Low-Dose CT Versus Chest Radiography in Screening for Lung Cancer
by Frei, Bradi; Bui, Christopher


8/1/2012
Methadone Dosing Regimen for Management of Iatrogenic Opioid Abstinence Syndrome in Critically Ill Children
by Nazer, Lama


8/1/2012
Medication Reconciliation for Safer Patient Care
by Saliba, Adeline


8/1/2012
The Unfolding ATLAS in Secondary Prevention of Acute Coronary Syndrome
by Andres, Jennifer; Clements, Jennifer


8/1/2012
To Add or Not To Add, Is There a Role for Purine Analogues in AML 7+3?
by Alotaibi, Ghazi


7/24/2012
Analgosedation for Mechanically Ventilated Patients
by Nazer, Lama


7/18/2012
Daptomycin versus Vancomcyin for Methicillin-Resistant Staphylococcus aureus Bloodstream Infection with Elevated Vancomycin Minimum Inhibitory Concent
by El-Lababidi, Rania


7/18/2012
Feature: Is Linezolid Superior To Vancomycin?—Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia
by Tabayoyong, Leo


7/18/2012
Haloperidol Prophylaxis Decreases Delirium Incidence in Elderly Patients after Non-Cardiac Surgery
by Al-Qadheeb, Nada


7/2/2012
When Blood is not Thicker than Water: Rivaroxaban Use in the Treatment of Pulmonary Embolism
by Fairall, Keith; Havrda, Dawn


7/2/2012
Meta-Analysis of New Oral Anticoagulants versus Warfarin in Patients with AF
by Alotaibi, Ghazi; Al-Almodaimegh, Hind


7/2/2012
Unwrapping the Benefit of Chocolate Consumption in Cardiometabolic Disorders
by Perez, Criselle; Linn, William


6/28/2012
The Risk of Bladder Cancer Associated with Pioglitazone (Actos®)
by Zobeck, Bryan


6/21/2012
Novel Therapy in Dyslipidemia Therapy: CETP Inhibitor Evacetrapib
by Falter, Rebecca


6/21/2012
Triple Antithrombotic Therapy in STEMI Patients After PCI: A Reason to Stay Up at Night?
by Lalama, Jeffrey


6/21/2012
LESS is MORE - Psychological Long-Term Effects of a No-Sedation Protocol in Critically Ill Patients
by Al-Qadheeb, Nada


6/14/2012
Encounter Frequency and Serum Glucose Level, Blood Pressure, and Cholesterol Level Control in Patients with Diabetes Mellitus1
by Parvizi, Derek; Masters, Kelly


6/8/2012
A Potential Role of Pharmacists in the Patient-Center Medical Home
by Ball, Ryan; Clements, Jennifer


5/21/2012
AIM-HIGH in Dyslipidemia Therapy: Is There an Added Benefit to Raising HDL?
by Falter, Rebecca


5/21/2012
Apixaban: How Good Is It?—ARISTOTLE Trial
by Tabayoyong, Leo


5/7/2012
Impact of Concurrent Antibiotics on the Treatment of Clostridium Difficile Infection
by Ploetz, Jeannette


About the Editors
William D. Linn, PharmD
Founding Editor
William D. Linn, PharmD, is the Assistant Dean and Chair of the Department of Pharmacy Practice in the Feik School of Pharmacy at the University of the Incarnate Word. He is also the senior editor of Pharmacotherapy in Primary Care, and has served as a clinical specialist in primary care for over twenty years at the South Texas Veterans Health Care System.
Dawn Havrda, PharmD, FCCP, BCPS
Senior Editor
Dawn E. Havrda, Pharm.D., FCCP, BCPS is a Professor and Chair of the Department of Pharmacy Practice in the Bernard J. Dunn School of Pharmacy at Shenandoah University. She is also a clinical pharmacist at Amherst Family Practice where she cares for patients with diabetes, hypertension, cardiovascular disorders, and chronic anticoagulation, as well as provides medication therapy management and assists patients with Medicare Part D.
Nada Al-Qadheeb, PharmD, BCPS, FCCP
Editor
Dr. Al-Qadheeb is a clinical specialist in the Medical and Surgical intensive care unit at King Faisal Specialist Hospital and Research Center (KFSH&RC). She received a BS degree in pharmacy from King Saud University, Riyadh, Saudi Arabia and the Doctor of Pharmacy from University of Maryland, Baltimore. Dr. Al-Qadheeb completed a specialty residency in Critical Care from The Johns Hopkins Hospital, Baltimore. She is board certified in pharmacotherapy and a fellow of the American College of Chest Physicians. She is the recipient of the Dumez Lecture Award for superior professionalism in pharmacy from the University of Maryland, Baltimore. Dr. Al-Qadheeb has several national and international presentations. Her research interests focus on the areas of critical care and infectious diseases.