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Applied Biopharmaceutics & Pharmacokinetics, 6e Leon Shargel, Susanna Wu-Pong, Andrew B.C. Yu Preface     Copyright     Authors Glossary Chapter 1 Introduction to Biopharmaceutics and Pharmacokinetics Chapter 2 Mathematical Fundamentals in Pharmacokinetics Chapter 3 One-Compartment Open Model: Intravenous Bolus Administration Chapter 4 Multicompartment Models: Intravenous Bolus Administration Chapter 5 Intravenous Infusion Chapter 6 Drug Elimination and Clearance Chapter 7 Pharmacokinetics of Oral Absorption Chapter 8 Multiple-Dosage Regimens Chapter 9 Nonlinear Pharmacokinetics Chapter 10 Physiologic Drug Distribution and Protein Binding Chapter 11 Drug Elimination and Hepatic Clearance Chapter 12 Pharmacogenetics Chapter 13 Physiologic Factors Related to Drug Absorption Chapter 14 Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance Chapter 15 Drug Product Performance, In Vivo: Bioavailability and Bioequivalence Chapter 16 Impact of Drug Product Quality and Biopharmaceutics on Clinical Efficacy Chapter 17 Modified-Release Drug Products Chapter 18 Targeted Drug Delivery Systems and Biotechnological Products Chapter 19 Relationship between Pharmacokinetics and Pharmacodynamics Chapter 20 Application of Pharmacokinetics to Clinical Situations Chapter 21 Dose Adjustment in Renal and Hepatic Disease Chapter 22 Physiologic Pharmacokinetic Models, Mean Residence Time, and Statistical Moment Theory Appendix A: Statistics Appendix B: Applications of Computers in Pharmacokinetics Appendix C: Solutions to Frequently Asked Questions (FAQs) and Learning Questions Appendix D: Guiding Principles for Human and Animal Research1 Appendix E: Popular Drugs and Pharmacokinetic Parameters