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Harper's Illustrated Biochemistry, 29e Chapter 53. Metabolism of Xenobiotics Sections: Objectives, Biomedical Importance, Humans Encounter Thousands of Xenobiotics that Must Be Metabolized before Being Excreted, Isoforms of Cytochrome P450 Hydroxylate a Myriad of Xenobiotics in Phase 1 of Their Metabolism, Conjugation Reactions Prepare Xenobiotics for Excretion in Phase 2 of Their Metabolism, The Activities of Xenobiotic-Metabolizing Enzymes Are Affected by Age, Sex, & Other Factors, Responses to Xenobiotics Include Pharmacologic, Toxic, Immunologic, & Carcinogenic Effects, Pharmacogenomics Will Drive the Development of New & Safer Drugs, Summary, References. Topics Discussed: biotransformation of xenobiotics; xenobiotics. Excerpt:"After studying this chapter, you should be able to:..."
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