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Harper's Illustrated Biochemistry, 29e
Chapter 47. Glycoproteins
Sections: Objectives, Biomedical Importance, Glycoproteins Occur Widely & Perform Numerous Functions, Oligosaccharide Chains Encode Biologic Information, Techniques Are Available for Detection, Purification, Structural Analysis & Synthesis of Glycoproteins, Eight Sugars Predominate in Human Glycoproteins, Nucleotide Sugars Act as Sugar Donors in Many Biosynthetic Reactions, Exo- & Endoglycosidases Facilitate Study of Glycoproteins, The Mammalian Asialoglycoprotein Receptor Is Involved in Clearance of Certain Glycoproteins from Plasma by Hepatocytes, Lectins Can Be Used to Purify Glycoproteins & to Probe Their Functions, There Are Three Major Classes of Glycoproteins, Glycoproteins Contain Several Types of O-Glycosidic Linkages, N-Linked Glycoproteins Contain an Asn-GLcNAc Linkage, Some Proteins Are Anchored to the Plasma Membrane by Glycophosphatidylinositol Structures, Advanced Glycation End-Products (AGEs) Are Thought to Be Important in the Causation of Tissue Damage in Diabetes Mellitus, Glycoproteins Are Involved in Many Biologic Processes & in Many Diseases, The Glycans of Glycoconjugates Are Involved in the Binding of Viruses, Bacteria & Certain Parasites to Human Cells, The Pace of Research in Glycomics Is Accelerating, Summary, References.
Topics Discussed: glycoprotein.
Excerpt:"After studying this chapter, you should be able to:..."
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